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 Intro & Faculty
6th CACHEXIA CONFERENCE
8-10 December 2011
Milan, Italy
Chairmen:
Giuseppe Rosano, Rome, Italy
Filippo Rossi Fanelli, Rome, Italy
Akio Inui, Kagoshima, Japan
Stefan D. Anker, Berlin, Germany
William J. Evans, Research Triangle Park, NC, USA
John E. Morley, St. Louis, MO, USA
Organization:
Society on Sarcopenia, Cachexia
and Wasting Disorders (SCWD)
C/O MedEd GS
75, rue Guy Môquet
92240 Malakoff - France
Phone: +33 1 42 53 03 03
Fax: +33 1 42 53 03 02
Email: SCWD@mededgs.com
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Topics:
CACHEXIA IN MANY ILLNESSES
• Cancer
• Chronic heart failure
• Chronic kidney disease
• COPD
• Liver cirrhosis
• Infections: AIDS and Sepsis
CACHEXIA AND SARCOPENIA
Pathophysiology and Biochemistry of Cachexia
• Regulation of food intake
• Proteolysis and muscle wasting
• Lipolytic pathways
• Apoptosis and autophagy
• Neurohormonal activation
• Symptom generation (anorexia, fatigue, shortness of breath)
THERAPIES
• SARMs and other anabolics
• Nutrition and essential aminoacids
• Proteasome inhibitors
• Appetite stimulants
• Anti-catabolic therapies
• Anti-inflammatory therapies
• Exercise
• Myostatin-targeting therapies
• Late-breaking trial results
• Late-breaking science
CONSENSUS DEVELOPMENT AND DEBATES
• Cachexia defi nition consensus
• Designing clinical trials in cachexia: endpoints
• Nutrition versus drugs
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December 2010 Trialist Workshop program, Washington, USA
